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Year : 2022  |  Volume : 12  |  Issue : 2  |  Page : 67-68

Acute asthma exacerbation after SARS-CoV-2 vaccine (Sinovac®): a case report

Department of Pulmonology, Akdeniz University School of Medicine, Antalya, Turkey

Correspondence Address:
Fatih Uzer
Department of Pulmonology, Akdeniz University School of Medicine, Antalya
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2045-9912.326003

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A 76-year-old female received a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine (CoronaVac, Sinovac®, Beijing, China) and subsequently experienced chest discomfort. A computed tomography performed 1 day after vaccination showed multiple infiltrations in both lungs and ground-glass shadows in both lung fields. Her fingertip oxygen saturation was 81% and there was widespread wheezing on physical examination. Based on these findings, the patient was hospitalized with a preliminary diagnosis of drug-induced pneumonitis and acute asthma exacerbation due to a SARS-CoV-2 vaccine. During her hospitalization, 40 mg/d systemic steroid, 4 times a day salbutamol nebulized, 2 L/min inhaled oxygen therapy and 400 mg/d moxifloxacin intravenous were administered for 5 days. One month later, the thorax computed tomography scan revealed that the previous findings were almost completely regressed.

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